He holds undergraduate and masters degrees in business from Wayne State University in Detroit, and he received his Ph.D. in marketing from Northwestern University. Coventry University welcomes International Students. She received her undergraduate business degree from the University of Prince Edward Island, her MBA from Saint Mary’s University, and her Ph.D. in marketing from the University of Alberta. Associate Pro-Vice-Chancellor (International Business Development)+44 (0) 24 7715 2173Gary.Armstrong@coventry.ac.uk, Kate Gillman+44 (0) 797 498 4082Kate.gillman@coventry.ac.uk. We use the migratory desert locust (Locusta migratoria), an animal naturally exposed to harsh condition... A prior hyperthermic stress (heat shock) can induce thermoprotection of neuromuscular transmission in Locusta migratoria extensor tibiae muscle measured 4 h after the onset of the heat shock. preclinical stages of the disease. ALS related mutations using Zebrafish as an model animal. Overview. All rights reserved. He completed an MBA in International Business at Coventry University in 2011. Animal models of the disease suggest that significant neuronal abnormalities exist during Here you will find information about term dates for both new and returning students as well as study break and end of semester dates for undergraduate and postgraduate students. Despite considerable research attention focused on mechanisms underlying neural spreading depression (SD), because of its association with important human CNS pathologies, such as stroke and migraine, little attention has been given to explaining its occurrence and regulation in invertebrates. Neuromuscular junction abnormalities in a zebrafish loss-of-function model of TDP-43, Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model, Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis, Augmented quantal release of acetylcholine at the vertebrate neuromuscular junction following TDP-43 depletion, Homology Directed Knockin of Point Mutations in the Zebrafish tardbp and fus Genes in ALS Using the CRISPR/Cas9 System, Fishing for causes and cures of motor neuron disorders, Na+-K+-ATPase trafficking induced by heat shock pretreatment correlates with increased resistance to anoxia in locusts, Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS, Calcium Channel Agonists Protect against Neuromuscular Dysfunction in a Genetic Model of TDP-43 Mutation in ALS, Cold hardening modulates K+ homeostasis in the brain of Drosophila melanogaster during chill coma, Glial Hsp70 Protects K+ Homeostasis in the Drosophila Brain during Repetitive Anoxic Depolarization, Compositions and methods for treating neural anoxia and spreading depression, Metabolic Stress Modulates Motor Patterning via AMP-Activated Protein Kinase, Coma in response to environmental stress in the locust: A model for cortical spreading depression, Inhibition of protein kinase G activity protects neonatal mouse respiratory network from hyperthermic and hypoxic stress, Suppression of Spreading Depression-Like Events in Locusts by Inhibition of the NO/cGMP/PKG Pathway, Stress Preconditioning of Spreading Depression in the Locust CNS, Natural Variation in the Thermotolerance of Neural Function and Behavior due to a cGMP-Dependent Protein Kinase, Octopamine Mediates Thermal Preconditioning of the Locust Ventilatory Central Pattern Generator via a cAMP/Protein Kinase A Signaling Pathway, A role for octopamine in coordinating thermoprotection of an insect nervous system, Rapid neural thermoprotection using PKG inhibition, A role for the cytoskeleton in heat-shock-mediated thermoprotection of locust neuromuscular junctions, Department of Ecology and Evolutionary Biology, Département Sclérose latérale amyotrophique (SLA) et neuromusculaire. It is not clear what effect an acute hyperthermic stress may have on the nervous system's ability to tolerate thermal stress, that is, before increased expres... Join ResearchGate to find the people and research you need to help your work. (WMV). Gary is responsible for the development and implementation of the University’s trans-national education strategy and international student mobility. University students and faculty, institute members, and independent researchers, Technology or product developers, R&D specialists, and government or NGO employees in scientific roles, Health care professionals, including clinical researchers, Journalists, citizen scientists, or anyone interested in reading and discovering research. The locust (Locusta migratoria) responds to anoxia by entering a coma during which neural and muscular systems shut down. Dr. Gary Armstrong is by far the most amazing professor that I have ever had, and is definitely someone that you want fighting in your corner. Gary Armstrong is Assistant Professor in the Department of Neurology and Neurosurgery at the Montreal Neurological Institute and a Killam Scholar. A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. CANADIAN AUTHOR: VALERIE TRIFTS is a professor of marketing at Dalhousie University, Rowe School of Business, in Halifax. spinal cord and cerebral cortex. Cortical spreading depression (CSD) is closely associated with important pathologies including stroke, seizures and migraine. Publishers of technology books, eBooks, and videos for creative people. He has been very active in the teaching and administration of Kenan-Flagler's undergraduate program. We investigated the effects of energetic compromise in Drosophila by targeting the Na(+)/K(+)-ATPase. Spreading depression (SD) is an interesting and important phenomenon due to its role in mammalian pathologies such as migraine, seizures, and stroke. He holds undergraduate and masters degrees in business from Wayne State University in Detroit, and he received his Ph.D. in marketing from Northwestern University. The degree of the [K+]o disturbance was the same in CON and HS locusts. CANADIAN AUTHOR: VALERIE TRIFTS is a professor of marketing at Dalhousie University, Rowe School of Business, in Halifax. Different hypotheses exist about the underlying disease... Amyotrophic lateral sclerosis (ALS) is a rapidly progressing, fatal disorder with no effective treatment. He has also received the Charles Coolidge Parlin Award, which each year honors an outstanding leader in the field of marketing. Gary is responsible for the development and implementation of the University’s trans-national education strategy and international student mobility. We examined the effect of a heat shock pretreatment (HS) on the sensitivity of the locust (Locusta migratoria) nervous system to anoxia induced by water immersion. We measured the thermosensitivity of central pattern generation in response to a ramped increase of temper... Neural function is susceptible to failure under heat stress but protective measures taken by the central nervous system (CNS) in particular organisms offer a level of protection that allows neural function to be maintained at higher temperatures. Dr Gary Armstrong has been a Senior Lecturer in Criminology at City, University of London since 2018. The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 type II (Cas9) system has emerged as a simple and inexpensive tool for editing genomic loci of i... Motor neuron disorders (MNDs) are a clinically heterogeneous group of neurological diseases characterized by progressive degeneration of motor neurons, and share some common pathological pathways. Following a career at Barclays Bank, he joined the University as deputy director for international operations in 2009. © 2020 Pearson Education, Peachpit. He has consulted with many major U.S. and foreign companies in the areas of marketing strategy and planning, marketing organization, and international marketing.